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APCDD1 Protein (AA 27-492)

APCDD1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
N° du produit ABIN7504233
  • Antigène Voir toutes APCDD1 Protéines
    APCDD1 (Adenomatosis Polyposis Coli Down-Regulated 1 (APCDD1))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 27-492
    Origine
    • 5
    • 1
    • 1
    • 1
    Humain
    Source
    • 4
    • 2
    • 2
    HEK-293 Cells
    Fonction
    Human APCDD1 Protein
    Séquence
    Leu27-His492
    Attributs du produit
    Recombinant Human APCDD1 Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Leu27-His492.
    Pureté
    > 95 % as determined by Tris-Bis PAGE
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product APCDD1 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    APCDD1 (Adenomatosis Polyposis Coli Down-Regulated 1 (APCDD1))
    Autre désignation
    APCDD1 (APCDD1 Produits)
    Synonymes
    drapc1 Protein, xPgo Protein, APCDD1 Protein, Pgo1 Protein, cAPCDD1 Protein, B7323 Protein, DRAPC1 Protein, HHS Protein, HTS Protein, AB023957 Protein, AU041258 Protein, Drapc1 Protein, EIG180 Protein, adenomatosis polyposis coli down-regulated 1 Protein, APC down-regulated 1 Protein, adenomatosis polyposis coli down-regulated 1 L homeolog Protein, apcdd1 Protein, APCDD1 Protein, Apcdd1 Protein, apcdd1.L Protein
    Sujet
    Adenomatosis polyposis coli downregulated 1 (APCDD1), a negative regulator of Wnt signaling, was examined to understand detailed mechanisms underlying Wnt signaling tooth development. In situ hybridization showed that Apcdd1 was expressed in the condensed mesenchyme at the bud stage, and in the inner enamel epithelium (IEE), including enamel knot (EK) at the cap stage. APCDD1 modulates the gene expression of Wnt- and EK-related signaling molecules at the cap stage of tooth development, and is involved in tooth cusp patterning by modulating the epithelial rearrangement in the IEE.
    Poids moléculaire
    80.06 kDa. Due to glycosylation, the protein migrates to 82-110 kDa based on Tris-Bis PAGE result.
    UniProt
    Q8J025
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