MME Protein (AA 52-750)

N° du produit ABIN7504255

Détail du produit

Antigène: MME (Membrane Metallo-Endopeptidase (MME))

Type de proteíne: Recombinant

Attributs du protein: AA 52-750

Origine: Humain

Source: HEK-293 Cells

Fonction: Human CD10/MME Protein

Séquence: Tyr52-Trp750

Attributs du produit: Recombinant Human CD10/MME Protein is expressed from HEK293 without tag.It contains Tyr52-Trp750.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied as 0.22 μm filtered solution in 50 mM MES, 100 mM NaCl, 10 % glycerol ( pH 6.5).

Stock: -80 °C

Stockage commentaire: Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: MME (Membrane Metallo-Endopeptidase (MME))

Autre désignation: CD10 (MME Produits)

Synonymes: CALLA Protein, CD10 Protein, NEP Protein, SFE Protein, 6030454K05Rik Protein, C85356 Protein, Nep Protein, neprilysin Protein, membrane metalloendopeptidase Protein, membrane metallo endopeptidase Protein, membrane metallo-endopeptidase Protein, MME Protein, Mme Protein

Sujet: CD10 is an endopeptidase that degrades various bioactive peptides in the extracellular matrix. In addition to enzymatic degradation, it affects multiple intracellular signal transduction pathways. CD10 expression has been extensively studied in human epithelial cancers of numerous organs and sites. CD10 expression pattern depended on the histotypes of thyroid lesions. When possible metastatic tumours and non-epithelial tumours are excluded, high CD10 expression may be useful in determining whether a primary thyroid carcinoma includes an anaplastic component.

Poids moléculaire: 79.83 kDa. Due to glycosylation, the protein migrates to 80-100 kDa based on Tris-Bis PAGE result.

UniProt: P08473

Pathways: Signalisation RTK, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration