HLA-A*02:01 (Monomer) protein (Biotin,MAGE-A2)

N° du produit ABIN7504361

Détail du produit

Antigène: HLA-A*02:01

Type de proteíne: Recombinant

Attributs du protein: Monomer

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Biotin,MAGE-A2

Fonction: Biotinylated Human HLA-A*02:01 & B2M & MAGE-A2 (KMVELVHFL) Monomer Protein

Séquence: Gly25-Thr305 (HLA-A*02:01), Ile21-Met119 (B2M) and KMVELVHFL peptide

Specificité: Uni-Prot: A0A140T913 (HLA-A*02:01), P61769 (B2M), KMVELVHFL

Attributs du produit: Recombinant Biotinylated Human HLA-A*02:01 & B2M & MAGE-A2 (KMVELVHFL) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KMVELVHFL peptide.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: HLA-A*02:01

Sujet: Melanoma antigen gene (MAGE)-A2 (MAGEA2) is a member of the MAGE-A family proteins widely studied for cancer vaccine development and identification of tumor markers. MAGEA2 plays an oncogenic role in glioma progression, and they provide insight into MAGEA2 application as a novel predictor of clinical outcomes and a potential glioma biomarker.

Poids moléculaire: 50.50 kDa. Due to glycosylation, the protein migrates to 52-62 kDa based on Tris-Bis PAGE result.

UniProt: A0A140T913