HLA-A*02:01 (Monomer) protein (Biotin,MAGE-A3)

N° du produit ABIN7504362

Détail du produit

Antigène: HLA-A*02:01

Type de proteíne: Recombinant

Attributs du protein: Monomer

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Biotin,MAGE-A3

Fonction: Biotinylated Human HLA-A*02:01 & B2M & MAGE-A3 (KVAELVHFL) Monomer Protein

Séquence: Gly25-Thr305 (HLA-A*02:01), Ile21-Met119 (B2M) and KVAELVHFL peptide

Specificité: Uni-Prot: A0A140T913 (HLA-A*02:01), P61769 (B2M), KVAELVHFL

Attributs du produit: Recombinant Biotinylated Human HLA-A*02:01 & B2M & MAGE-A3 (KVAELVHFL) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305 (HLA-A*02:01), Ile21-Met119 (B2M) and KVAELVHFL peptide.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: HLA-A*02:01

Sujet: Melanoma antigen family A, 3 (MAGE-A3) is a cancer-testis antigen whose expression has been demonstrated in a wide array of malignancies including melanoma, brain, breast, lung and ovarian cancer. In addition, its ability to elicit spontaneous humoral and cellular immune responses has been shown in cancer patients.

Poids moléculaire: 50.50 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Tris-Bis PAGE result.

UniProt: A0A140T913