HLA-A*02:01 (Monomer) protein (MAGE-A10)

N° du produit ABIN7504370

Détail du produit

Antigène: HLA-A*02:01

Type de proteíne: Recombinant

Attributs du protein: Monomer

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: MAGE-A10

Fonction: Human HLA-A*02:01 & B2M & MAGE-A10 (GLYDGMEHL) Monomer Protein

Séquence: Gly25-Thr305 (HLA-A*02:01), Ile21-Met119 (B2M) and GLYDGMEHL peptide

Specificité: Uni-Prot: A0A140T913 (HLA-A*02:01), P61769 (B2M), GLYDGMEHL

Attributs du produit: Recombinant Human HLA-A*02:01 & B2M & MAGE-A10 (GLYDGMEHL) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and GLYDGMEHL peptide.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied as 0.22 μm filtered solution in PBS ( pH 7.4).

Stock: -80 °C

Stockage commentaire: Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: HLA-A*02:01

Sujet: MAGE-A10 is a subtype of the Melanoma-associated antigen A (MAGE-A), a class of tumor antigens that are extensively expressed in various histological types of tumors and represents an attractive target for tumor immunotherapy. High-level expression of MAGE-A10 improved the anti-tumor immune cytotoxicity of MAGE-A10-specific CTLs in lung cancer cell lines and primary lung cancer cells.

Poids moléculaire: 50.44 kDa. Due to glycosylation, the protein migrates to 53-63 kDa based on Tris-Bis PAGE result.

UniProt: A0A140T913