Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
Stock
-80 °C
Stockage commentaire
Valid for 12 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Date de péremption
12 months
Antigène
IL1F10
(Interleukin 1 Family, Member 10 (Theta) (IL1F10))
FIL1-theta Protein, IL-1HY2 Protein, IL-38 Protein, IL1-theta Protein, IL1HY2 Protein, interleukin 1 family, member 10 Protein, interleukin 1 family member 10 Protein, Il1f10 Protein, IL1F10 Protein
Sujet
Interleukin (IL)-38, a newly discovered IL-1 family cytokine, is expressed in several tissues and secreted by various cells. IL-38 has recently been reported to exert an anti-inflammatory function by binding to several receptors, including interleukin-36 receptor (IL-36R), interleukin-1 receptor accessory protein-like 1 (IL-1RAPL1), and interleukin-1 receptor 1 (IL-1R1) to block binding with other pro-inflammatory cytokines and inhibit subsequent signaling pathways, thereby regulating the differentiation and function of T cells, peripheral blood mononuclear cells, macrophages, and dendritic cells.
Poids moléculaire
18.64 kDa. The protein migrates to 20-25 kDa based on Tris-Bis PAGE result.