PUMA Protein (AA 1-193) (His tag)

N° du produit ABIN7504951

Détail du produit

Antigène: PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))

Type de proteíne: Recombinant

Attributs du protein: AA 1-193

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PUMA protéine est marqué à la His tag.

Application: Immunogen (Imm)

Séquence: Met1-Asn193

Attributs du produit: A DNA sequence encoding the Human PUMA/BBC3 (Q9BXH1-1) (1M-193N) was expressed with a polyhistidine tag at the N-terminus.

Pureté: > 90 % as determined by reducing SDS-PAGE.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

used as Immunogen for (ABIN6999884, ABIN7234184, ABIN7234185 and ABIN7234186)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))

Autre désignation: PUMA (BBC3 Produits)

Synonymes: BBC3 Protein, Puma Protein, JFY-1 Protein, JFY1 Protein, PUMA Protein, PUMA/JFY1 Protein, BCL2 binding component 3 Protein, Bcl-2 binding component 3 Protein, BBC3 Protein, Bbc3 Protein, bbc3 Protein

Sujet:

Abbreviation: PUMA,BBC3

Target Synonym: BBC 3,Bbc3,BBC3_HUMAN,BCL 2 binding component 3,Bcl-2-binding component 3,BCL2 binding component 3,JFY 1,JFY-1,JFY1,p53 up regulated modulator of apoptosis,p53 up-regulated modulator of apoptosis,p53 Upregulated Modulator of Apoptosis,PUMA alpha,PUMA/JFY1

Background: Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis . Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis.

Poids moléculaire:

Calculated MW: 20.1 kDa

Observed MW: 20-24 kDa

UniProt: Q9BXH1-1

Pathways: Signalisation p53, Positive Regulation of Endopeptidase Activity