Liver Arginase Protein (AA 1-322) (His tag)
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- Antigène Voir toutes Liver Arginase (ARG1) Protéines
- Liver Arginase (ARG1) (Arginase, Liver (ARG1))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-322
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette Liver Arginase protéine est marqué à la His tag.
- Séquence
- Met1-Lys322
- Attributs du produit
- A DNA sequence encoding the human Arginase-1 (1M-322K) was expressed with a polyhistidine tag at the N-terminus.
- Pureté
- > 90 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product ARG1 Protéine
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Supplied as sterile solution of 25 mM Tris-HCl, 150 mM KCl, 1 mM DTT, 20 % glycerol, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Agent conservateur
- Dithiothreitol (DTT)
- Précaution d'utilisation
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- Liver Arginase (ARG1) (Arginase, Liver (ARG1))
- Autre désignation
- Arginase-1 (ARG1 Produits)
- Synonymes
- SI:zC146F4.4 (novel protein with NUDIX domain) Protein, si:ch211-146f4.3 Protein, argi1 Protein, AI Protein, AI256583 Protein, Arg-1 Protein, PGIF Protein, arginase 1 Protein, arginase Protein, Arginase-1 Protein, arginase, liver Protein, L-arginase Protein, arg1 Protein, PGTG_16455 Protein, argi1 Protein, ARG1 Protein, Arg1 Protein
- Sujet
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Abbreviation: Arginase-1
Target Synonym: ARG1,Al,Arginase 1,Arginase liver,
Background: Arginase 1, also known as liver arginase, is a binuclear manganese metalloenzyme. It is a key enzyme of the urea cycle that catalyses the conversion of L-arginine into L-ornithine and urea, the final cytosolic reaction of urea formation in the mammalian liver. Arginase 1 is abundantly expressed in liver, but it is also expressed in cells and tissues that lack a complete urea cycle, including lung.?Arginase is a critical regulator of nitric oxide synthesis and vascular function. It is implicated in a variety of human diseases including vascular disease, pulmonary disease, infectious disease, immune cell function and cancer. In humans, hereditary defects in arginase result in an accumulation of arginine in the blood known as hyperarginemia. Arginase deficiency can also result in the accumulation of nitrogen in the form of ammonia, which results in hyperammonemia.
- Poids moléculaire
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Calculated MW: 36.9 kDa
Observed MW: 38-40 kDa
- UniProt
- P05089
- Pathways
- Cellular Response to Molecule of Bacterial Origin
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