Uromodulin Protein (UMOD) (AA 25-587) (His tag)
-
- Antigène Voir toutes Uromodulin (UMOD) Protéines
- Uromodulin (UMOD)
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 25-587
-
Origine
- Humain
-
Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette Uromodulin protéine est marqué à la His tag.
- Séquence
- Asp25-Phe587
- Attributs du produit
- A DNA sequence encoding theHuman THP protein (P07911) (Asp25-Phe587) was expressed with a N-His.
- Pureté
- > 85 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product UMOD Protéine
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
-
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Date de péremption
- 12 months
-
- Antigène
- Uromodulin (UMOD)
- Autre désignation
- THP (UMOD Produits)
- Synonymes
- ADMCKD2 Protein, FJHN Protein, HNFJ Protein, HNFJ1 Protein, MCKD2 Protein, THGP Protein, THP Protein, urehr4 Protein, uromodulin Protein, UMOD Protein, Umod Protein
- Sujet
-
Abbreviation: THP
Target Synonym: Tamm-Horsfall urinary glycoprotein
Background: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure that may play a role in the water barrier permeability (Probable). May serve as a receptor for binding and endocytosis of cytokines (IL-1, IL-2) and TNF.Facilitates neutrophil migration across renal epithelia.
- Poids moléculaire
-
Calculated MW: 61.4 kDa
Observed MW: 50 kDa
- UniProt
- P07911
-