S100B Protein (AA 2-92) (GST tag)
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- Antigène Voir toutes S100B Protéines
- S100B (S100 Calcium Binding Protein B (S100B))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 2-92
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette S100B protéine est marqué à la GST tag.
- Séquence
- Ser2-Glu92
- Attributs du produit
- A DNA sequence encoding theHuman S100B protein (P04271) (Ser2-Glu92) was expressed with a N-GST.
- Pureté
- > 90 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product S100B Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Date de péremption
- 12 months
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- Antigène
- S100B (S100 Calcium Binding Protein B (S100B))
- Autre désignation
- S100B (S100B Produits)
- Synonymes
- NEF Protein, S100 Protein, S100-B Protein, S100beta Protein, S100P Protein, AI850290 Protein, Bpb Protein, si:dkey-110p14.2 Protein, wu:fq18b10 Protein, zgc:92776 Protein, S100 calcium binding protein B Protein, S100 protein, beta polypeptide, neural Protein, S100 calcium binding protein, beta (neural) Protein, S100B Protein, S100b Protein, s100b Protein
- Sujet
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Abbreviation: S100B
Target Synonym: S-100 protein beta chain,S-100 protein subunit beta,S100 calcium-binding protein B
Background: Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
- Poids moléculaire
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Calculated MW: 36.6 kDa
Observed MW: 37 kDa
- UniProt
- P04271
- Pathways
- Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins
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