BMPR2 Protein (AA 27-150) (His tag)
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- Antigène Voir toutes BMPR2 Protéines
- BMPR2 (Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 27-150
- Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette BMPR2 protéine est marqué à la His tag.
- Séquence
- Ser27-Thr150
- Attributs du produit
- A DNA sequence encoding theHuman BMPR2 protein (Q13873) (Ser27-Thr150) was expressed with a N-His.
- Pureté
- > 85 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product BMPR2 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Date de péremption
- 12 months
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- Antigène
- BMPR2 (Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))
- Autre désignation
- BMPR2 (BMPR2 Produits)
- Synonymes
- BMPR-II Protein, BMPR3 Protein, BMR2 Protein, BRK-3 Protein, PPH1 Protein, T-ALK Protein, 2610024H22Rik Protein, AL117858 Protein, AW546137 Protein, BB189135 Protein, BMP-2 Protein, BMPR-2 Protein, BMPRII Protein, Gm20272 Protein, Bmpr-II Protein, bmprii Protein, bone morphogenetic protein receptor type 2 Protein, bone morphogenetic protein receptor, type II b (serine/threonine kinase) Protein, bone morphogenetic protein receptor, type II (serine/threonine kinase) Protein, BMPR2 Protein, bmpr2b Protein, Bmpr2 Protein
- Sujet
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Abbreviation: BMPR2
Target Synonym: BMP type-2 receptor,BMPR-2,Bone morphogenetic protein receptor type II,BMP type II receptor,BMPR-II
Background: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.
- Poids moléculaire
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Calculated MW: 26 kDa
Observed MW: 35 kDa
- UniProt
- Q13873
- Pathways
- Growth Factor Binding
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