NEFM Protein (AA 2-358) (GST tag)

N° du produit ABIN7505037

Détail du produit

Antigène: NEFM (Neurofilament Triplet M Protein (NEFM))

Type de proteíne: Recombinant

Attributs du protein: AA 2-358

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette NEFM protéine est marqué à la GST tag.

Séquence: Ser 2-Ser 358

Attributs du produit: A DNA sequence encoding the Human NEF3 protein (P07197) (Ser2-Ser358) was expressed with a GST.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: NEFM (Neurofilament Triplet M Protein (NEFM))

Autre désignation: NEF3 (NEFM Produits)

Synonymes: NEF3 Protein, NF-M Protein, NFM Protein, Nef3 Protein, Nfm Protein, NF160 Protein, NF165 Protein, nef-m Protein, nef3 Protein, nefm Protein, nf-m Protein, zgc:112359 Protein, nefm-a Protein, nefm-b Protein, neurofilament medium Protein, neurofilament triplet M protein Protein, neurofilament, medium polypeptide Protein, neurofilament medium polypeptide Protein, neurofilament medium L homeolog Protein, neurofilament, medium polypeptide a Protein, neurofilament medium S homeolog Protein, NEFM Protein, Nefm Protein, TVAG_582010 Protein, TVAG_379630 Protein, nefm.L Protein, nefma Protein, nefm.S Protein

Sujet:

Abbreviation: NEF3

Target Synonym: Neurofilament medium polypeptide,NF-M,160 kDa neurofilament protein,Neurofilament 3,Neurofilament triplet M protein,NEFM,NEF3,NFM

Background: Human NF-M (neurofilament-medium length) is a 145?150 kDa phosphorylated glycoprotein that belongs to the type IV intermediate filament family. It is 915 amino acids in length and contains a 100 amino acid (aa) N-terminal globular region, a 320 aa alpha -helical rod, or central region, and a 500 aa globular tail. The rod region contains a series of heptad repeats that contribute to a coiled-coil interaction with an adjacent NF-M molecule, the first step in intermediate filament oligomerization. The C-terminus shows phosphorylation and O-linked glycosylation. Human NF-M aa 2?358, which includes most of the rod region, shares ~98 % aa sequence identity with corresponding region of mouse, rat and canine NF-M.

Poids moléculaire:

Calculated MW: 64.16 kDa

Observed MW: 60 kDa

UniProt: P07197

Pathways: Brown Fat Cell Differentiation