Ataxin 2 Protein (ATXN2) (AA 460-600) (GST tag)
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- Antigène Voir toutes Ataxin 2 (ATXN2) Protéines
- Ataxin 2 (ATXN2)
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 460-600
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette Ataxin 2 protéine est marqué à la GST tag.
- Séquence
- Leu 460-Ser 600
- Attributs du produit
- A DNA sequence encoding the Human ATXN2 protein (Q99700) (Leu460-Ser600) was expressed with a N-GST tag.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product ATXN2 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Date de péremption
- 12 months
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- Antigène
- Ataxin 2 (ATXN2)
- Autre désignation
- ATXN2 (ATXN2 Produits)
- Synonymes
- ASL13 Protein, ATX2 Protein, SCA2 Protein, TNRC13 Protein, 9630045M23Rik Protein, AW544490 Protein, Sca2 Protein, ATXN2 Protein, MGC115230 Protein, ataxin 2 Protein, ataxin 2 L homeolog Protein, ATXN2 Protein, Atxn2 Protein, atxn2.L Protein
- Sujet
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Abbreviation: ATXN2
Target Synonym: Ataxin-2,Spinocerebellar ataxia type 2 protein,Trinucleotide repeat-containing gene 13 protein,ATXN2,ATX2,SCA2,TNRC13
Background: Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane.Expressed in the brain, heart, liver, skeletal muscle, pancreas and placenta. Isoform 1 is predominant in the brain and spinal cord. Isoform 4 is more abundant in the cerebellum. In the brain, broadly expressed in the amygdala, caudate nucleus, corpus callosum, hippocampus, hypothalamus, substantia nigra, subthalamic nucleus and thalamus.
- Poids moléculaire
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Calculated MW: 40.4 kDa
Observed MW: 42 kDa
- UniProt
- Q99700
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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