UCP1 Protein (AA 1-307) (His tag)

N° du produit ABIN7505050

Détail du produit

Antigène: UCP1 (Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-307

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette UCP1 protéine est marqué à la His tag.

Séquence: Met 1-Thr 307

Attributs du produit: A DNA sequence encoding the Human UCP1 protein (P25874) (Met 1-Thr 307) was expressed with a N-His tag.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: UCP1 (Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1))

Autre désignation: UCP1 (UCP1 Produits)

Synonymes: ARABIDOPSIS THALIANA PLANT UNCOUPLING MITOCHONDRIAL PROTEIN 1 Protein, ARABIDOPSIS THALIANA UNCOUPLING PROTEIN 1 Protein, ATPUMP1 Protein, ATUCP1 Protein, UCP Protein, UCP1 Protein, UNCOUPLING PROTEIN 1 Protein, plant uncoupling mitochondrial protein 1 Protein, ucp Protein, slc25a7 Protein, SLC25A7 Protein, AI385626 Protein, Slc25a7 Protein, Ucp Protein, Ucpa Protein, Uncp Protein, plant uncoupling mitochondrial protein 1 Protein, uncoupling protein 1 Protein, uncoupling protein 1 L homeolog Protein, uncoupling protein 1 (mitochondrial, proton carrier) Protein, PUMP1 Protein, UCP1 Protein, ucp1.L Protein, ucp1 Protein, Ucp1 Protein

Sujet:

Abbreviation: UCP1

Target Synonym: UCP1,SLC25A7,UCP

Background: Mitochondrial brown fat uncoupling protein 1 (UCP1, also Thermogenin and UCP) is a 33 kDa member of the mitochondrial carrier family of proteins. Human UCP1 are both 307 amino acids (aa) in length and contain three solcar repetitive regions and six transmembrane segments. UCP1 is found in brown adipose tissue, where it becomes activated by fatty acids and inhibited by nucleotides. It functions as a mitochondrial transporter that creates a proton leak across the inner mitochondrial membrane, uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.

Poids moléculaire:

Calculated MW: 33.66 kDa

Observed MW: 31 kDa

UniProt: P25874

Pathways: Proton Transport, Brown Fat Cell Differentiation