PIGR Protein (AA 19-561) (His tag)

N° du produit ABIN7505062

Détail du produit

Antigène: PIGR (Polymeric Immunoglobulin Receptor (PIGR))

Type de proteíne: Recombinant

Attributs du protein: AA 19-561

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PIGR protéine est marqué à la His tag.

Séquence: Lys 19-Ala 561

Attributs du produit: A DNA sequence encoding the Human PIGR/SC protein (P01833) (Lys 19-Ala 561) was expressed with a N-His tag.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: PIGR (Polymeric Immunoglobulin Receptor (PIGR))

Autre désignation: PIGR (PIGR Produits)

Synonymes: DKFZp469G1013 Protein, RNPIGR2 Protein, pIgA-R Protein, polymeric immunoglobulin receptor Protein, PIGR Protein, Pigr Protein

Sujet:

Abbreviation: PIGR;SC

Target Synonym: Polymeric Immunoglobulin Receptor;PIgR;Poly-Ig Receptor;PIGR

Background: Polymeric immunoglobulin receptor, also known as PIGR, is a member of the immunoglobulin superfamily and a Fc receptor. The ectodomain of this receptor consists of five units with homology to the variable units of immunoglobulins and a transmembrane region, which also has some homology to certain immunoglobulin variable regions. PIGR is expressed on several glandular epithelia including those of liver and breast. The deduced amino-acid sequence has a length of 764 residues and shows an overall similarity of 56% and 64% with the rabbit and rat counterpart. PIGR mediates transcellular transport of polymeric immunoglobulin molecules, and thus facilitates the secretion of IgA and IgM. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment of PIGR.

Poids moléculaire:

Calculated MW: 59.62 kDa

Observed MW: 59 kDa

UniProt: P01833