PPARD Protein (AA 260-426) (His tag)
-
- Antigène Voir toutes PPARD Protéines
- PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 260-426
-
Origine
- Humain
-
Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette PPARD protéine est marqué à la His tag.
- Séquence
- Leu260-Glu426
- Attributs du produit
- A DNA sequence encoding the Human PPAR-δ protein (Q03181) (Leu260-Glu426) was expressed with a N-His .
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product PPARD Protéine
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
-
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Date de péremption
- 12 months
-
- Antigène
- PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))
- Autre désignation
- PPAR-delta (PPARD Produits)
- Synonymes
- FAAR Protein, NR1C2 Protein, NUC1 Protein, NUCI Protein, NUCII Protein, PPARB Protein, NUC-1 Protein, Nr1c2 Protein, PPAR-beta Protein, PPAR-delta Protein, PPAR[b] Protein, PPARdelta Protein, Pparb Protein, Pparb/d Protein, PPARBETA Protein, ppard Protein, pparb Protein, PPARD Protein, PPAR-D/B Protein, peroxisome proliferator activated receptor delta Protein, peroxisome proliferator activator receptor delta Protein, peroxisome proliferator activated receptor delta S homeolog Protein, peroxisome proliferator-activated receptor delta Protein, PPARD Protein, Ppard Protein, ppard.S Protein, ppard Protein
- Sujet
-
Abbreviation: PPAR-delta
Target Synonym: Peroxisome proliferator-activated receptor delta,PPAR-delta,NUCI,Nuclear hormone receptor 1,NUC1,Nuclear receptor subfamily 1 group C member 2,Peroxisome proliferator-activated receptor beta,PPAR-beta,NR1C2,PPARB
Background: Ligand-activated transcription factor key mediator of energy metabolism in adipose tissues.Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand
- Poids moléculaire
-
Calculated MW: 18.26 kDa
Observed MW: 20 kDa
- UniProt
- Q03181
- Pathways
- Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Monocarboxylic Acid Catabolic Process, Smooth Muscle Cell Migration, Positive Regulation of fat Cell Differentiation
-