PNLIP Protein (AA 245-465) (His tag)

N° du produit ABIN7505074

Détail du produit

Antigène: PNLIP (Pancreatic Lipase (PNLIP))

Type de proteíne: Recombinant

Attributs du protein: AA 245-465

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PNLIP protéine est marqué à la His tag.

Séquence: Pro 245-Cys 465

Attributs du produit: A DNA sequence encoding the Human PL protein (P16233) (Pro245-Cys465) was expressed with a N-His .

Pureté: > 95 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: PNLIP (Pancreatic Lipase (PNLIP))

Autre désignation: Pancreatic lipase (PNLIP Produits)

Synonymes: PL Protein, PNLIPD Protein, PTL Protein, LIPASE Protein, PANLI Protein, 1810007A24Rik Protein, PNLIP Protein, PNLIPRP2 Protein, pancreatic lipase Protein, PNLIP Protein, Pnlip Protein, pnlip Protein

Sujet:

Abbreviation: Pancreatic lipase,PL

Target Synonym: Pancreatic triacylglycerol lipase,PL,PTL,Pancreatic lipase,PNLIP

Background: PNLIP is an enzyme which belongs to the lipase family. Secreted from the pancreas, PNLIP is the primary lipase that hydrolyzes dietary fat molecules in the human digestive system, converting triglyceride substrates found in ingested oils to monoglycerides and free fatty acids. Bile salts secreted from the liver and stored in gallbladder are released into the duodenum where they coat and emulsify large fat droplets into smaller droplets, thus increasing the overall surface area of the fat, which allows the lipase to break apart the fat more effectively. The resulting monomers (2 free fatty acids and one 2-monoacylglycerol) are then moved by way of peristalsis along the small intestine to be absorbed into the lymphatic system by a specialized vessel called a lacteal.

Poids moléculaire:

Calculated MW: 24.2 kDa

Observed MW: 30 kDa

UniProt: P16233