GIP Protein (AA 22-153) (His tag)

N° du produit ABIN7505083

Détail du produit

Antigène: GIP (Gastric Inhibitory Polypeptide (GIP))

Type de proteíne: Recombinant

Attributs du protein: AA 22-153

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette GIP protéine est marqué à la His tag.

Séquence: Glu 22-Arg 153

Attributs du produit: A DNA sequence encoding the Human GIP protein (P09681) (Glu 22-Arg 153) was expressed with a N-His tag.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: GIP (Gastric Inhibitory Polypeptide (GIP))

Autre désignation: GIP (GIP Produits)

Synonymes: GIP Protein, xgip Protein, Gludins Protein, RATGLUDINS Protein, gastric inhibitory polypeptide Protein, gastric inhibitory polypeptide L homeolog Protein, GIP Protein, gip Protein, Gip Protein, gip.L Protein

Sujet:

Abbreviation: GIP

Target Synonym: gastric inhibitory polypeptide,GIP,Glucose-dependent Insulinotropic Polypeptide,Incretin

Background: Gastric inhibitory polypeptide (GIP), also known as the glucose-dependent insulinotropic peptide is a member of the secretin family of hormones. GIP, together with glucagon-like peptide-1 (GLP-1), belongs to the group of metabolic hormones called incretins that stimulate a decrease in blood glucose levels. GIP is derived from a 153-amino acid pro-protein encoded by the GIP gene and circulates as a biologically active 42-amino acid peptide. Engagement of Gastric inhibitory polypeptide receptors (GIPR) by GIP on pancreatic beta cells activates adenylate cyclase to regulate insulin compensation in the presence of high circulating glucose.

Poids moléculaire:

Calculated MW: 14.41 kDa

Observed MW: 18 kDa

UniProt: P09681

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism