Periostin Protein (POSTN) (AA 97-230) (His tag)

N° du produit ABIN7505095

Détail du produit

Antigène: Periostin (POSTN)

Type de proteíne: Recombinant

Attributs du protein: AA 97-230

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Periostin protéine est marqué à la His tag.

Séquence: Pro 97-Leu 230

Attributs du produit: A DNA sequence encoding the Human POSTN/OSF-2 protein (Q15063) (Pro 97-Leu 230) was expressed with a N-His tag.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: Periostin (POSTN)

Autre désignation: POSTN (POSTN Produits)

Synonymes: fa99h07 Protein, pn Protein, postn Protein, wu:fa99h07 Protein, wu:fc70f09 Protein, zgc:153873 Protein, LOC100008945 Protein, osf-2 Protein, pdlpostn Protein, periostin Protein, OSF-2 Protein, OSF2 Protein, PDLPOSTN Protein, PN Protein, RP11-412K4.1 Protein, A630052E07Rik Protein, AI747096 Protein, Osf2 Protein, PLF Protein, peri Protein, Plf Protein, periostin Protein, periostin, osteoblast specific factor b Protein, periostin, osteoblast specific factor Protein, POSTN Protein, postnb Protein, postn Protein, Postn Protein

Sujet:

Abbreviation: POSTN,OSF-2

Target Synonym: Osteoblast-specific factor 2,OSF-2,POSTN,Periostin,PDLPOSTN,periostin,PN

Background: Periostin ( POSTN ), also known as OSF2 (osteoblast specific factor 2), is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesion and movement, as well as collagen fibrillogenesis. Postn is expressed in unique growth centers during embryonic development where it facilitates epithelial-mesenchymal transition (EMT) of select cell populations undergoing reorganization. In the adult, Postn expression is specifically induced in areas of tissue injury or areas with ongoing cellular re-organization. In the adult heart Postn is induced in the ventricles following myocardial infarction, pressure overload stimulation, or generalized cardiomyopathy. Although the detailed function of Postn is still unclear, Postn-integrin interaction is thought to be involved in tumor development. Postn is frequently overexpressed in various types of human cancers, stimulating metastatic growth by promoting cancer cell survival, invasion and angiogenesis, and can be a useful marker to predict the behavior of cancer.

Poids moléculaire:

Calculated MW: 14.63 kDa

Observed MW: 15 kDa

UniProt: Q15063