SQSTM1 Protein (AA 3-102) (His tag)
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- Antigène Voir toutes SQSTM1 Protéines
- SQSTM1 (Sequestosome 1 (SQSTM1))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 3-102
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette SQSTM1 protéine est marqué à la His tag.
- Séquence
- Ser 3-Lys 102
- Attributs du produit
- A DNA sequence encoding the Human SQSTM1 protein (Q13501) (Ser 3-Lys 102) was expressed with a N-His tag.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product SQSTM1 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Date de péremption
- 12 months
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- Antigène
- SQSTM1 (Sequestosome 1 (SQSTM1))
- Autre désignation
- SQSTM1 (SQSTM1 Produits)
- Synonymes
- SQSTM1 Protein, sqstm1 Protein, MGC79491 Protein, A170 Protein, OSIL Protein, PDB3 Protein, ZIP3 Protein, p60 Protein, p62 Protein, p62B Protein, OSF-6 Protein, Osi Protein, STAP Protein, ZIP Protein, sb:cb621 Protein, zgc:85784 Protein, sequestosome 1 Protein, sequestosome 1 L homeolog Protein, SQSTM1 Protein, sqstm1 Protein, Sqstm1 Protein, sqstm1.L Protein
- Sujet
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Abbreviation: SQSTM1,p62
Target Synonym: A170,DMRV,EBI 3 associated protein p60,EBIAP,FTDALS3,ORCA,OSF-6,OSIL,p60,P62b,PDB 3,PDB3,Sequestosome 1,SQSTM 1,STAP,STONE14,ZIP3
Background: Adapter protein which binds ubiquitin and may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels.
- Poids moléculaire
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Calculated MW: 10.89 kDa
Observed MW: 15 kDa
- UniProt
- Q13501
- Pathways
- Signalisation NF-kappaB, Neurotrophin Signaling Pathway, Autophagy
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