FLT3LG Protein (AA 27-184) (His tag)

N° du produit ABIN7505168

Détail du produit

Antigène: FLT3LG (Fms-Related tyrosine Kinase 3 Ligand (FLT3LG))

Type de proteíne: Recombinant

Attributs du protein: AA 27-184

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette FLT3LG protéine est marqué à la His tag.

Séquence: Thr 27-Pro 184

Attributs du produit: A DNA sequence encoding the Human FLT3LG protein (P49771) (Thr 27-Pro 184) was expressed with N-His tag.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: FLT3LG (Fms-Related tyrosine Kinase 3 Ligand (FLT3LG))

Autre désignation: FLT3LG (FLT3LG Produits)

Synonymes: Flt3lg Protein, Ly72L Protein, FL Protein, FLT3L Protein, Vegfr3 Protein, fms related tyrosine kinase 3 ligand Protein, FMS-like tyrosine kinase 3 ligand Protein, fms-related tyrosine kinase 4 Protein, fms-related tyrosine kinase 3 ligand Protein, FLT3LG Protein, Flt3l Protein, Flt4 Protein, Flt3lg Protein

Sujet:

Abbreviation: FLT3LG,Flt3 ligand

Target Synonym: Fms-Felated Tyrosine Kinase 3 Ligand,Flt3 Ligand,Flt3L,SL Cytokine,FLT3LG

Background: FLT3L, also known as flt3 ligand, is a small molecule that acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. In vivo, FLT3L also induces the mobilization of the hematopoietic progenitors and stem cells. This may help the system to kill cancer cells. Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3L controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 -positive classical DCs and their CD103 -positive tissue counterparts.

Poids moléculaire:

Calculated MW: 17.27 kDa

Observed MW: 21 kDa

UniProt: P49771

Pathways: Signalisation RTK