L-Selectin Protein (AA 39-332) (His tag)

N° du produit ABIN7505200

Détail du produit

Antigène: L-Selectin (SELL) (Selectin L (SELL))

Type de proteíne: Recombinant

Attributs du protein: AA 39-332

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette L-Selectin protéine est marqué à la His tag.

Séquence: Trp 39-Asn 332

Attributs du produit: A DNA sequence encoding the Human CD62L/L-Selectin protein (P30836) (Trp 39-Asn 332) was expressed with N-His tag.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: L-Selectin (SELL) (Selectin L (SELL))

Autre désignation: CD62L (SELL Produits)

Synonymes: CD62L Protein, LAM1 Protein, LECAM1 Protein, LEU8 Protein, LNHR Protein, LSEL Protein, LYAM1 Protein, PLNHR Protein, TQ1 Protein, A.11 Protein, L-selectin Protein, LECAM-1 Protein, SELE Protein, AI528707 Protein, Lnhr Protein, Ly-22 Protein, Ly-m22 Protein, Lyam-1 Protein, Lyam1 Protein, selectin L Protein, selectin, lymphocyte Protein, SELL Protein, Sell Protein

Sujet:

Abbreviation: CD62L,L-Selectin

Target Synonym: L-selectin,Sell,CD62 antigen-like family member L,Leukocyte adhesion molecule 1 (LAM-1),Leukocyte-endothelial cell adhesion molecule 1,Lymph node homing receptor,Lymphocyte antigen 22 (Ly-22),Lymphocyte surface MEL-14 antigen,CD62L

Background: L-Selectin (also known as Leukocyte Selectin, LAM?1, LECAM-1, LECCAM-1, TQ1, Leu-8, MEL-14 antigen, DREG, lymph node homing receptor, CD62L), a member of the Selectin family, is a cell surface glycoprotein expressed constitutively on a wide variety of leukocytes. Two forms of L?Selectin have been reported, apparently arising as a result of post-translational modifications. The lymphocyte form shows an apparent molecular weight of 74 kDa, while the neutrophil form is 90 - 100 kDa. Human and mouse L?Selectin share 76 % amino acid (aa) sequence homology.L?Selectin plays a role in the migration of lymphocytes into peripheral lymph nodes and sites of chronic inflammation, and of neutrophils into acute inflammatory sites. Acting in cooperation with P-Selectin and E-Selectin, L?Selectin mediates the initial interaction of circulating leukocytes with endothelial cells that produces a characteristic "rolling" of the leukocytes on the endothelium. This initial interaction, also involving ICAM-1 and VCAM-1, leads eventually to extravasation of the white blood cell through the blood vessel wall into the extracellular matrix tissue.

Poids moléculaire:

Calculated MW: 32.23 kDa

Observed MW: 39 kDa

UniProt: P30836