SLAMF1 Protein (AA 21-237) (His tag)

N° du produit ABIN7505204

Détail du produit

Antigène: SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

Type de proteíne: Recombinant

Attributs du protein: AA 21-237

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette SLAMF1 protéine est marqué à la His tag.

Séquence: Ala 21-Pro 237

Attributs du produit: A DNA sequence encoding the Human SLAMF1/CD150 / SLAM protein (Q13291) (Ala 21-Pro 237) was expressed with N-His tag.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

Autre désignation: CD150 (SLAMF1 Produits)

Synonymes: CD150 Protein, SLAM Protein, SLAMF1 Protein, 4933415F16 Protein, AA177906 Protein, CDw150 Protein, ESTM51 Protein, IPO-3 Protein, Slam Protein, RGD1560634 Protein, signaling lymphocytic activation molecule family member 1 Protein, SLAMF1 Protein, Slamf1 Protein

Sujet:

Abbreviation: CD150,SLAMF1

Target Synonym: Signaling Lymphocytic Activation Molecule,CDw150,IPO-3,CD150,SLAMF1,SLAM

Background: CD150/signaling lymphocytic activation molecule (SLAM) is a cell surface sialylated phosphoglycoprotein and belongs to the CD2 subset of the Ig superfamily of type I transmembrane glycoproteins. The CD150 receptor is expressed on thymocytes, activated and memory T cells, B cells, platelets, natural killer T cells, and mature dendritic cells, and is also detected on tumor cells of Hodgkin's lymphoma (HL) and diffuse large B-cell lymphoma with an activated B cell phenotype. Additionally, it is the immune cell receptor for measles virus (MV). As a self-ligand, CD150 performs diverse immunologic functions including T/B-cell costimulation, induction of IFN-&gamma in Th1 T-cell clones, redirection of Th2 clones to a Th1 or Th0 phenotype, and inhibition of apoptosis in B cells. Furthermore, CD150 was shown to be the second receptor for measles virus in addition to CD46, and the distribution of SLAM on various cell lines is consistent with their susceptibility to clinical isolates of measles virus.

Poids moléculaire:

Calculated MW: 23.76 kDa

Observed MW: 30 kDa

UniProt: Q13291