RCAS1 Protein (AA 28-213) (His tag)

N° du produit ABIN7505209

Détail du produit

Antigène: RCAS1 (EBAG9) (Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9))

Type de proteíne: Recombinant

Attributs du protein: AA 28-213

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette RCAS1 protéine est marqué à la His tag.

Séquence: Arg 28-Ser 213

Attributs du produit: A DNA sequence encoding the Human RCAS1 / EBAG9 protein (O00559) (Arg 28-Ser 213) was expressed with N-His.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: RCAS1 (EBAG9) (Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9))

Autre désignation: RCAS1 (EBAG9 Produits)

Synonymes: EB9 Protein, PDAF Protein, MGC56608 Protein, zgc:56608 Protein, MGC84425 Protein, EBAG9 Protein, AI835379 Protein, Rcas1 Protein, RCAS1 Protein, eb9 Protein, pdaf Protein, rcas1 Protein, estrogen receptor binding site associated, antigen, 9 Protein, estrogen receptor binding site associated, antigen, 9 L homeolog Protein, estrogen receptor-binding fragment-associated gene 9 Protein, EBAG9 Protein, ebag9 Protein, ebag9.L Protein, Ebag9 Protein

Sujet:

Abbreviation: RCAS1,EBAG9

Target Synonym: Receptor-binding cancer antigen expressed on SiSo cells,EBAG9,RCAS1,Cancer-associated surface antigen RCAS1,Estrogen receptor-binding fragment-associated gene 9 protein

Background: RCAS1, also known as EBAG9, is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. RCAS1 gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor which binds to the estrogen-responsive element (ERE) found in the 5'-flanking region of RCAS1 gene. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for RCAS1 gene. EBAG9 may participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.

Poids moléculaire:

Calculated MW: 20.35 kDa

Observed MW: 39 kDa

UniProt: O00559