RAB11A Protein (AA 2-212) (His tag)

N° du produit ABIN7505258

Détail du produit

Antigène: RAB11A (RAB11A, Member RAS Oncogene Family (RAB11A))

Type de proteíne: Recombinant

Attributs du protein: AA 2-212

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette RAB11A protéine est marqué à la His tag.

Séquence: Gly 2-Cys 212

Attributs du produit: A DNA sequence encoding the Human RAB11A protein (P62491) (Gly 2-Cys 212) was expressed with a N-His&C-His tag.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: RAB11A (RAB11A, Member RAS Oncogene Family (RAB11A))

Autre désignation: RAB11A (RAB11A Produits)

Synonymes: rab11 Protein, RAB11A Protein, wu:fi15h09 Protein, zgc:103679 Protein, yl8 Protein, Rab11a Protein, rab11A Protein, DDBDRAFT_0190819 Protein, DDBDRAFT_0191190 Protein, DDB_0190819 Protein, DDB_0191190 Protein, YL8 Protein, RAB11 Protein, RAB11A, member RAS oncogene family S homeolog Protein, RAB11A, member RAS oncogene family Protein, RAB11a, member RAS oncogene family Protein, Rab11 GTPase Protein, rab11A protein Protein, Rab11a, GTPase Protein, Rab GTPase Protein, rab11A, RAB family GTPase Protein, rab11a.S Protein, RAB11A Protein, rab11a Protein, Rab11a Protein, rab11A Protein

Sujet:

Abbreviation: RAB11A

Target Synonym: Ras-related protein Rab-11A,RAB11A,Rab-11

Background: Regulates endocytic recycling. May exert its functions by interacting with multiple effector proteins in different complexes. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial cell polarization. Together with RAB3IP, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis (By similarity). Together with MYO5B participates in CFTR trafficking to the plasma membrane and TF (Transferrin) recycling in nonpolarized cells. Required in a complex with MYO5B and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Participates in the sorting and basolateral transport of CDH1 from the Golgi apparatus to the plasma membrane. Regulates the recycling of FCGRT (receptor of Fc region of monomeric Ig G) to basolateral membranes.

Poids moléculaire:

Calculated MW: 23.1 kDa

Observed MW: 30 kDa

UniProt: P62491

Pathways: Regulation of Cell Size, Thromboxane A2 Receptor Signaling, Regulation of long-term Neuronal Synaptic Plasticity