PPP2CA Protein (AA 1-309) (His tag)

N° du produit ABIN7505262

Détail du produit

Antigène: PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))

Type de proteíne: Recombinant

Attributs du protein: AA 1-309

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PPP2CA protéine est marqué à la His tag.

Séquence: Met 1-Leu 309

Attributs du produit: A DNA sequence encoding the Human PP2A-Cα/PPP2CA protein (P67775) (Met 1-Leu 391) was expressed with a N-His&C-His tag.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))

Autre désignation: PP2A-Calpha (PPP2CA Produits)

Synonymes: PP2Ac Protein, PP2CA Protein, PP2Calpha Protein, RP-C Protein, PP2A Protein, R75353 Protein, Pp2a1 Protein, pp2ac Protein, zgc:110641 Protein, protein phosphatase 2 catalytic subunit alpha Protein, protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform Protein, protein phosphatase 2, catalytic subunit, alpha isozyme Protein, protein phosphatase 2 catalytic subunit alpha L homeolog Protein, protein phosphatase 2, catalytic subunit, beta isozyme Protein, serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Protein, PPP2CA Protein, Ppp2ca Protein, ppp2ca.L Protein, ppp2cb Protein, LOC471633 Protein, ppp2ca Protein

Sujet:

Abbreviation: PP2A-Cα,PPP2CA

Target Synonym: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform,PPP2CA, PP2A-alpha,Replication protein C (RP-C),PPP2CA

Background: Protein Phosphatase 2A (PP2A) is an enzyme that removes phosphates covalently attached to serine and threonine residues in proteins. It contains three subunits, a catalytic subunit C (PP2Ac), an assembly/structural subunit A (PP2Aa), and a regulatory subunit B (PP2Ab). PP2A is a ubiquitous enzyme that plays a role in regulating many cellular activities varying from ion transport in erythrocytes to suppressing tumor growth. Binding of the SV40 small T antigen to the PP2A phosphatase complex is known to cause oncogenic transformation.

Poids moléculaire:

Calculated MW: 39.3 kDa

Observed MW: 40 kDa

UniProt: P67775

Pathways: Signalisation PI3K-Akt, Mitotic G1-G1/S Phases, Hepatitis C, Toll-Like Receptors Cascades