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RBBP6 Protein (AA 1-313) (His tag)

RBBP6 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7505272
  • Antigène Tous les produits RBBP6
    RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-313
    Origine
    Humain
    Source
    • 2
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette RBBP6 protéine est marqué à la His tag.
    Séquence
    Met 1-Lys 313
    Attributs du produit
    A DNA sequence encoding the Human PACT protein (O75569) (Met 1-Lys 313) was expressed with a N-His&C-His tag.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Date de péremption
    12 months
  • Antigène
    RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))
    Autre désignation
    PACT (RBBP6 Produits)
    Synonymes
    MY038 Protein, P2P-R Protein, PACT Protein, RBQ-1 Protein, SNAMA Protein, 4933422O15Rik Protein, AI316869 Protein, BB233631 Protein, C030034J04Rik Protein, C77662 Protein, rbbp6 Protein, MGC75882 Protein, RBBP6 Protein, im:7158869 Protein, rbbp6l Protein, RB binding protein 6, ubiquitin ligase Protein, retinoblastoma binding protein 6, ubiquitin ligase Protein, retinoblastoma binding protein 6 Protein, RBBP6 Protein, Rbbp6 Protein, rbbp6 Protein
    Sujet

    Abbreviation: PACT

    Target Synonym: Interferon-inducible double-stranded RNA-dependent protein kinase activator A,PRKRA,PKR-associated protein X

    Background: Activates EIF2AK2/PKR in the absence of double stranded RNA (dsRNA), leading to phosphorylation of EIF2S1/EFI2-alpha and inhibition of translation and induction of apoptosis. Required for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing. Does not seem to be required for processing of pre-miRNA to miRNA by DICER1.

    Poids moléculaire

    Calculated MW: 34.32 kDa

    Observed MW: 38 kDa

    UniProt
    O75569
    Pathways
    Regulatory RNA Pathways
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