GAD Protein (AA 1-350) (His tag)
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- Antigène Voir toutes GAD (GAD1) Protéines
- GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-350
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette GAD protéine est marqué à la His tag.
- Séquence
- Met1-Try350
- Attributs du produit
- A DNA sequence encoding the Human GAD1GAD,GAD67 protein (Q99259) (Met1-Try350) was expressed with a C-His,N-His.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product GAD1 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Date de péremption
- 12 months
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- Antigène
- GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))
- Autre désignation
- GAD1GAD,GAD67 (GAD1 Produits)
- Synonymes
- CPSQ1 Protein, GAD Protein, SCP Protein, GAD-67 Protein, cpsq1 Protein, gad1 Protein, gad1-A Protein, gad67 Protein, GAD67 Protein, GAD1 Protein, GLUTAMATE DECARBOXYLASE Protein, GLUTAMATE DECARBOXYLASE 1 Protein, MKP11.30 Protein, MKP11_30 Protein, glutamate decarboxylase Protein, EP10 Protein, GAD25 Protein, GAD44 Protein, Gad-1 Protein, Gad67 Protein, glutamate decarboxylase 1 Protein, glutamate decarboxylase 1 L homeolog Protein, glutamate decarboxylase Protein, glutamate decarboxylase 1b Protein, GAD1 Protein, gad1.1.L Protein, GAD Protein, Gad1 Protein, gad1b Protein
- Sujet
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Abbreviation: GAD1GAD,GAD67
Target Synonym: CPSQ1;GAD;SCP
Background: Glutamate decarboxylase 1, also known as 67 kDa glutamic acid decarboxylase, Glutamate decarboxylase 67 kDa isoform and GAD1, is a member of the group II decarboxylase family. GAD1 is expressed in benign and malignant prostatic tissue and may serve as a highly prostate-specific tissue biomarker. GAD1 isoform 3 is expressed in pancreatic islets, testis, adrenal cortex, and perhaps other endocrine tissues, but not in brain. Tissue-specific markers are useful for identification of tumour type in advanced cancers of unknown origin. In plants, as in most eukaryotes, glutamate decarboxylase catalyses the synthesis of GABA. Root-specific calcium/calmodulin-regulated GAD1 plays a major role in GABA synthesis in plants under normal growth conditions and in response to stress. Defects in GAD1 are the cause of cerebral palsy spastic quadriplegic type 1 (CPSQ1)which is a non-progressive disorder of movement and/or posture resulting from defects in the developing central nervous system. Affected individuals manifest symmetrical, non-progressive spasticity and no adverse perinatal history or obvious underlying alternative diagnosis.
- Poids moléculaire
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Calculated MW: 38.39 kDa
Observed MW: 39 kDa
- UniProt
- Q99259-1
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