Fibronectin Protein (AA 32-230) (GST-His-Tag)

N° du produit ABIN7505313

Détail du produit

Antigène: Fibronectin

Type de proteíne: Recombinant

Attributs du protein: AA 32-230

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Fibronectin protéine est marqué à la GST-His-Tag.

Séquence: Gln 32-Arg 230

Attributs du produit: A DNA sequence encoding the Human Fibronectin protein (P02751) (Gln 32-Arg 230) was expressed with a N-GST&C-His tag.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: Fibronectin

Abstract: Fibronectin Produits

Synonymes: FN Protein, cig Protein, fibronectin Protein, finc Protein, lets Protein, msf Protein, CIG Protein, ED-B Protein, FINC Protein, FNZ Protein, GFND Protein, GFND2 Protein, LETS Protein, MSF Protein, E330027I09 Protein, Fn Protein, Fn-1 Protein, FIBNEC Protein, fn-1 Protein, fibronectin 1 Protein, FN1 Protein, fn1 Protein, Fn1 Protein

Sujet:

Abbreviation: Fibronectin

Target Synonym: Fibronectin,FN1,CIG,ED-B,FINC,FN,FNZ,GFND,GFND2,LETS,MSF

Background: Fibronectin is a high-molecular weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Similar to integrins, fibronectin binds extracellular matrix components such as collagen, fibrin, and heparan sulfate proteoglycans. Fibronectin plays a major role in cell adhesion, growth, migration, and differentiation, and it is important for processes such as wound healing and embryonic development. Altered fibronectin expression, degradation, and organization has been associated with a number of pathologies, including cancer and fibrosis. Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.

Poids moléculaire:

Calculated MW: 46.78 kDa

Observed MW: 50 kDa

UniProt: P02751