STEAP3 Protein (AA 1-258) (GST-His-Tag)
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- Antigène Voir toutes STEAP3 Protéines
- STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-258
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette STEAP3 protéine est marqué à la GST-His-Tag.
- Séquence
- Met1-Thr258
- Attributs du produit
- A DNA sequence encoding the Human STEAP3 protein (Q658P3) (Met1-Thr258) was expressed with a N-GST&C-His tag.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Date de péremption
- 12 months
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- Antigène
- STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))
- Autre désignation
- STEAP3 (STEAP3 Produits)
- Synonymes
- STEAP3 Protein, 1010001D01Rik Protein, Tsap6 Protein, pHyde Protein, AHMIO2 Protein, STMP3 Protein, TSAP6 Protein, dudlin-2 Protein, STEAP3 metalloreductase Protein, STEAP family member 3 Protein, STEAP3 Protein, steap3 Protein, Steap3 Protein
- Sujet
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Abbreviation: STEAP3
Target Synonym: Metalloreductase STEAP3,STEAP3,Six-transmembrane epithelial antigen of prostate 3
Background: Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NADP(+) as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.
- Poids moléculaire
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Calculated MW: 53.27 kDa
Observed MW: 55 kDa
- UniProt
- Q658P3
- Pathways
- Transition Metal Ion Homeostasis
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