Patched 1 Protein (PTCH1) (AA 122-436) (His tag)
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- Antigène Voir toutes Patched 1 (PTCH1) Protéines
- Patched 1 (PTCH1)
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 122-436
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette Patched 1 protéine est marqué à la His tag.
- Séquence
- Glu 122-Asp 436
- Attributs du produit
- A DNA sequence encoding the Human PTCH1 protein (Q13635) (Glu 122-Asp 436) was expressed with a N-His tag.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product PTCH1 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Date de péremption
- 12 months
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- Antigène
- Patched 1 (PTCH1)
- Autre désignation
- PTCH1 (PTCH1 Produits)
- Synonymes
- BCNS Protein, HPE7 Protein, NBCCS Protein, PTC Protein, PTC1 Protein, PTCH Protein, PTCH11 Protein, lep Protein, ptc1 Protein, ptc2 Protein, Ptch Protein, Ptch2 Protein, Ptc-1 Protein, XPtc1 Protein, patched Protein, patched1 Protein, A230106A15Rik Protein, Ptc Protein, Ptc1 Protein, mes Protein, patched 1 Protein, patched 1 L homeolog Protein, Protein patched homolog 1 Protein, PTCH1 Protein, ptch1 Protein, Ptch1 Protein, ptch1.L Protein, ptc-1 Protein
- Sujet
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Abbreviation: PTCH1
Target Synonym: Protein patched homolog 1,PTCH1,PTC,PTC1
Background: Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.
- Poids moléculaire
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Calculated MW: 34.54 kDa
Observed MW: 38 kDa
- UniProt
- Q13635
- Pathways
- Signalisation Hedgehog, Carbohydrate Homeostasis, Tube Formation
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