MME Protein (AA 461-750) (His tag)
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- Antigène Voir toutes MME Protéines
- MME (Membrane Metallo-Endopeptidase (MME))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 461-750
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Origine
- Souris
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette MME protéine est marqué à la His tag.
- Séquence
- Met 461-Trp 750
- Attributs du produit
- A DNA sequence encoding the Mouse MME protein (Q61391) (Met 461-Trp 750) was expressed with N-His tag.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product MME Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Date de péremption
- 12 months
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- Antigène
- MME (Membrane Metallo-Endopeptidase (MME))
- Autre désignation
- MME (MME Produits)
- Synonymes
- CALLA Protein, CD10 Protein, NEP Protein, SFE Protein, 6030454K05Rik Protein, C85356 Protein, Nep Protein, neprilysin Protein, membrane metalloendopeptidase Protein, membrane metallo endopeptidase Protein, membrane metallo-endopeptidase Protein, MME Protein, Mme Protein
- Sujet
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Abbreviation: MME,CD10,Neprilysin
Target Synonym: Atriopeptidase,CALLA,Enkephalinase,EPN,NEP,Neprilysin,neprilysin-390,neprilysin-411,SFE,Skin fibroblast elastase
Background: CD10, also known as neprilysin, common acute lymphoblastic leukemia antigen (CALLA), or neutral endopeptidase (NEP), is a zinc-dependent transmembrane metallo-endopeptidase. CD10 cleaves peptides at the N-terminal side of hydrophobic amino acid residues and deactivates a variety of signaling peptides. CD10 was shown to be one of the markers for a natural killer cell-restricted progenitor in fetal and adult tissues. Studies also suggest CD10 as a phenotypic marker to distinguish mature neutrophils from immature neutrophils in patients with inflammation. In addition, CD10+GPR77+ carcinoma-associated fibroblasts (CAFs) promote tumor formation and chemoresistance.
- Poids moléculaire
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Calculated MW: 31.79 kDa
Observed MW: 32 kDa
- UniProt
- Q61391
- Pathways
- Signalisation RTK, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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