Nerve Growth Factor Protein (NGF) (AA 122-241) (His tag)

N° du produit ABIN7505449

Détail du produit

Antigène: Nerve Growth Factor (NGF)

Type de proteíne: Recombinant

Attributs du protein: AA 122-241

Origine: Souris

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Nerve Growth Factor protéine est marqué à la His tag.

Séquence: Ser 122-Gly 241

Attributs du produit: A DNA sequence encoding the Mouse NGF/NGFB/beta-NGF protein (P01139) (Ser 122-Gly 241) was expressed with N-His tag.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: Nerve Growth Factor (NGF)

Autre désignation: NGF (NGF Produits)

Synonymes: Beta-NGF Protein, HSAN5 Protein, NGFB Protein, Ngfb Protein, ngfb Protein, ns:zft386 Protein, xx:zft386 Protein, zgc:109730 Protein, beta-NGF Protein, hsan5 Protein, beta-ngf Protein, NGF Protein, ngf Protein, nerve growth factor Protein, nerve growth factor b (beta polypeptide) Protein, nerve growth factor S homeolog Protein, NGF Protein, Ngf Protein, ngfb Protein, ngf Protein, ngf.S Protein

Sujet:

Abbreviation: NGF,NGFB,beta-NGF

Target Synonym: Beta-Nerve Growth Factor,Beta-NGF,NGF,NGFB

Background: NGF is the first member discovered in the Neurotrophin family, which includes brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Mouse beta -NGF is a homodimer of two 120 amino acid polypeptides. It shares approximately 90 % homology at the amino acid level with human beta -NGF and 95.8 % with rat beta -NGF. NGF signaling has been shown to play an important role in neuroprotection and repair. β-NGF acts as a growth and differentiation factor for B lymphocytes, and enhances B-cell survival. It is a potent neurotrophic factor that signals through its receptor β-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems.

Poids moléculaire:

Calculated MW: 13.09 kDa

Observed MW: 15 kDa

UniProt: P01139

Pathways: Regulation of Cell Size