Nerve Growth Factor Protein (NGF) (AA 122-241) (His tag)
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- Antigène Voir toutes Nerve Growth Factor (NGF) Protéines
- Nerve Growth Factor (NGF)
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 122-241
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Origine
- Souris
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette Nerve Growth Factor protéine est marqué à la His tag.
- Séquence
- Ser 122-Gly 241
- Attributs du produit
- A DNA sequence encoding the Mouse NGF/NGFB/beta-NGF protein (P01139) (Ser 122-Gly 241) was expressed with N-His tag.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product NGF Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Date de péremption
- 12 months
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- Antigène
- Nerve Growth Factor (NGF)
- Autre désignation
- NGF (NGF Produits)
- Synonymes
- Beta-NGF Protein, HSAN5 Protein, NGFB Protein, Ngfb Protein, ngfb Protein, ns:zft386 Protein, xx:zft386 Protein, zgc:109730 Protein, beta-NGF Protein, hsan5 Protein, beta-ngf Protein, NGF Protein, ngf Protein, nerve growth factor Protein, nerve growth factor b (beta polypeptide) Protein, nerve growth factor S homeolog Protein, NGF Protein, Ngf Protein, ngfb Protein, ngf Protein, ngf.S Protein
- Sujet
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Abbreviation: NGF,NGFB,beta-NGF
Target Synonym: Beta-Nerve Growth Factor,Beta-NGF,NGF,NGFB
Background: NGF is the first member discovered in the Neurotrophin family, which includes brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Mouse beta -NGF is a homodimer of two 120 amino acid polypeptides. It shares approximately 90 % homology at the amino acid level with human beta -NGF and 95.8 % with rat beta -NGF. NGF signaling has been shown to play an important role in neuroprotection and repair. β-NGF acts as a growth and differentiation factor for B lymphocytes, and enhances B-cell survival. It is a potent neurotrophic factor that signals through its receptor β-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems.
- Poids moléculaire
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Calculated MW: 13.09 kDa
Observed MW: 15 kDa
- UniProt
- P01139
- Pathways
- Regulation of Cell Size
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