S100B Protein (AA 2-92) (His tag)

N° du produit ABIN7505488

Détail du produit

Antigène: S100B (S100 Calcium Binding Protein B (S100B))

Type de proteíne: Recombinant

Attributs du protein: AA 2-92

Origine: Rat

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette S100B protéine est marqué à la His tag.

Séquence: Ser2-Glu92 LVPRGF Ser2-Glu92

Attributs du produit: A DNA sequence encoding theRat S100B protein (P04631) (Ser2-Glu92 LVPRGF Ser2-Glu92) was expressed with a N-His.

Pureté: > 90 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: S100B (S100 Calcium Binding Protein B (S100B))

Autre désignation: S100B (S100B Produits)

Synonymes: NEF Protein, S100 Protein, S100-B Protein, S100beta Protein, S100P Protein, AI850290 Protein, Bpb Protein, si:dkey-110p14.2 Protein, wu:fq18b10 Protein, zgc:92776 Protein, S100 calcium binding protein B Protein, S100 protein, beta polypeptide, neural Protein, S100 calcium binding protein, beta (neural) Protein, S100B Protein, S100b Protein, s100b Protein

Sujet:

Abbreviation: S100B

Target Synonym: S-100 protein beta chain,S-100 protein subunit beta,S100 calcium-binding protein B

Background: Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

Poids moléculaire:

Calculated MW: 21.9 kDa

Observed MW: 28 kDa

UniProt: P04631

Pathways: Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins