Angiopoietin 1 Protein (ANGPT1) (AA 304-450) (His tag)

N° du produit ABIN7505509

Détail du produit

Antigène: Angiopoietin 1 (ANGPT1)

Type de proteíne: Recombinant

Attributs du protein: AA 304-450

Origine: Rat

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Angiopoietin 1 protéine est marqué à la His tag.

Séquence: Asn304-Ala450

Attributs du produit: A DNA sequence encoding the Rat ANG1 protein (O35460) (Asn304-Ala450) was expressed with a N-His .

Pureté: > 95 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: Angiopoietin 1 (ANGPT1)

Autre désignation: Angiopoietin-1 (ANGPT1 Produits)

Synonymes: AGP1 Protein, AGPT Protein, ANG1 Protein, 1110046O21Rik Protein, Ang-1 Protein, Ang1 Protein, Agpt Protein, Agpt1 Protein, ang1 Protein, wu:fc76g06 Protein, ANG-1 Protein, angpt1 Protein, MGC80788 Protein, angiopoietin 1 Protein, angiopoietin 1 S homeolog Protein, ANGPT1 Protein, Angpt1 Protein, angpt1 Protein, angpt1.S Protein

Sujet:

Abbreviation: Angiopoietin-1,ANG1

Target Synonym: AGP1,AGPT,Ang1,ANG-1,angiopoietin 1,Angiopoietin-1,ANGPT1,ANGP1_RAT

Background: Angiopoietin-1 (Ang-1) is a secreted glycoprotein that plays a critical role in the development and maintenance of the vascular system. The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. Angiopoietin-1 can protect against pulmonary arterial hypertension, reduce the extent of fibrosis and remodeling in infarcted diabetic myocardium, and enhance tumor progression and metastasis.

Poids moléculaire:

Calculated MW: 16.06 kDa

Observed MW: 18 kDa

UniProt: O35460

Pathways: Signalisation RTK, Glycosaminoglycan Metabolic Process