IL28B Protein (AA 19-192) (His tag)

N° du produit ABIN7505532

Détail du produit

Antigène: IL28B (Interleukin 28B (Interferon, lambda 3) (IL28B))

Type de proteíne: Recombinant

Attributs du protein: AA 19-192

Origine: Rat

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette IL28B protéine est marqué à la His tag.

Séquence: His 19-Ala 192

Attributs du produit: A DNA sequence encoding the Rat IL-28B/IFN-lambda-3 protein (F1M3K4) (His 19-Ala 192) was expressed with N-His tag.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: IL28B (Interleukin 28B (Interferon, lambda 3) (IL28B))

Autre désignation: IL-28B (IL28B Produits)

Synonymes: Il28b Protein, IFL-1 Protein, IL-28B Protein, INF-alpha Protein, INF-lambda Protein, Il28 Protein, IL28B Protein, IL28C Protein, interferon, lambda 3 Protein, interferon lambda 3 Protein, Ifnl3 Protein, IFNL3 Protein

Sujet:

Abbreviation: IL-28B,IFN-lambda-3

Target Synonym: Interleukin-28B,IL-28B,Cytokine Zcyto22,Interferon Lambda-3,IFN-Lambda-3,Interferon Lambda-4,IFN-Lambda-4,Interleukin-28C,IL-28C,IL28B,IFNL3,IFNL4,IL28C,ZCYTO22

Background: Interleukin-28B, also known as Cytokine Zcyto22, Interferon lambda-3, Interferon lambda-4, IFNL3, IFNL4, ZCYTO22 and IL28B, is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to play a role in the adaptive immune response. IL28B has immunomodulatory activity and up-regulates MHC class I antigen expression. IL28B displays potent antiviral activity and antitumor activity. In addition, IL28B is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.

Poids moléculaire:

Calculated MW: 19.03 kDa

Observed MW: 25 kDa

UniProt: F1M3K4