FGA Protein (AA 37-258) (His tag)
-
- Antigène Voir toutes FGA Protéines
- FGA (Fibrinogen alpha Chain (FGA))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 37-258
-
Origine
- Rat
-
Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette FGA protéine est marqué à la His tag.
- Séquence
- Gly 37-Met 258
- Attributs du produit
- A DNA sequence encoding the Rat FGA protein (P06399) (Gly 37-Met 258) was expressed with N-His tag.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product FGA Protéine
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
-
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Date de péremption
- 12 months
-
- Antigène
- FGA (Fibrinogen alpha Chain (FGA))
- Autre désignation
- FGA (FGA Produits)
- Synonymes
- Fib2 Protein, ENSMUSG00000059807 Protein, Fib Protein, Ac1873 Protein, Fba5e Protein, fibrinogen alpha chain Protein, FGA Protein, Fga Protein, LOC698244 Protein
- Sujet
-
Abbreviation: FGA
Target Synonym: FGA,Fib2,Fibrinogen A,Fibrinogen alpha chain,Fibrinogen Type I,fibrinogen,A alpha polypeptide,FPA
Background: Fibrinogen is a 340 kDa, secreted glycoprotein complex that is found in blood at concentrations of 150-400 mg/dL. It is secreted primarily by hepatocytes, but is also reported to be expressed by fibroblasts, type I alveolar epithelium, intestinal epithelium and some tumor cells. Fibrinogen is a homodimer that is composed of two, three-polypeptide chain subunits. Fibrinogen plays a central role in clot formation. Conversion of fibrinogen to fibrin is triggered by thrombin, which cleaves fibrinopeptides A and B from alpha and beta chains, and thus exposes the N-terminal polymerization sites responsible for the formation of the soft clot. The soft clot is converted into the hard clot by factor XIIIA which catalyzes the epsilon-(gamma-glutamyl)lysine cross-linking between gamma chains (stronger) and between alpha chains (weaker) of different monomers. Fibrinogen is also a component of the ECM and binds to cell surface molecules on inflammatory cells.
- Poids moléculaire
-
Calculated MW: 24.31 kDa
Observed MW: 30 kDa
- UniProt
- P06399
-