GSTM2 Protein (AA 2-218) (His tag)

N° du produit ABIN7505544

Détail du produit

Antigène: GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))

Type de proteíne: Recombinant

Attributs du protein: AA 2-218

Origine: Rat

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette GSTM2 protéine est marqué à la His tag.

Séquence: Pro 2-Lys 218

Attributs du produit: A DNA sequence encoding the Rat GSTM2 protein (P08010) (Pro 2-Lys 218) was expressed with N-His tag.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))

Autre désignation: GSTM2 (GSTM2 Produits)

Synonymes: GSTA4 Protein, GST4 Protein, GSTM Protein, GSTM2-2 Protein, GTHMUS Protein, Gstb-2 Protein, Gstb2 Protein, GSTIV Protein, glutathione S-transferase mu 2 Protein, glutathione S-transferase mu 2 (muscle) Protein, glutathione S-transferase Mu 2 Protein, glutathione S-transferase, mu 2 Protein, glutathione S-transferase 2 Protein, Glutathione S-transferase 4 Protein, Gstm2 Protein, GSTM2 Protein, LOC100732167 Protein, gst2 Protein, gst-4 Protein

Sujet:

Abbreviation: GSTM2

Target Synonym: GST4;GSTM;GSTM2-2;GTHMUS

Background: Glutathione S-transferase Mu 2, also known as GST class-mu 2, GSTM2-2 and GSTM2, is a cytoplasm protein which belongs to the GST superfamily and Mu family. GSTM2 / GST4 contains one GST C-terminal domain and one GST N-terminal domain. The glutathione S-transferases (GSTs) are a multigene family of enzymes largely involved in the detoxification of chemicals. Eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. Butyrate, an important luminal component produced from fermentation of dietary fibers, is an efficient inducer of GSTs and especially of GSTM2. Butyrate may act chemoprotectively by increasing detoxification capabilities in the colon mucosa.

Poids moléculaire:

Calculated MW: 23.76 kDa

Observed MW: 30 kDa

UniProt: P08010

Pathways: Negative Regulation of Transporter Activity