Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

CD22 Protein (AA 24-331) (His tag)

CD22 Origine: Rat Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7505557
  • Antigène Voir toutes CD22 Protéines
    CD22 (CD22 Molecule (CD22))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 24-331
    Origine
    • 23
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Rat
    Source
    • 22
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette CD22 protéine est marqué à la His tag.
    Séquence
    Trp 24-Thr 331
    Attributs du produit
    A DNA sequence encoding the Rat CD22/Siglec-2 protein (D3ZD88) (Trp 24-Thr 331) was expressed with N-His.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product CD22 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Date de péremption
    12 months
  • Antigène
    CD22 (CD22 Molecule (CD22))
    Autre désignation
    CD22 (CD22 Produits)
    Synonymes
    A530093D23 Protein, Lyb-8 Protein, Lyb8 Protein, SIGLEC-2 Protein, SIGLEC2 Protein, siglec-2 Protein, CD22 antigen Protein, CD22 molecule Protein, Cd22 Protein, CD22 Protein
    Sujet

    Abbreviation: CD22,Siglec-2

    Target Synonym: CD22 antigen,Cd22,

    Background: Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins, one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.

    Poids moléculaire

    Calculated MW: 33.77 kDa

    Observed MW: 39 kDa

    UniProt
    D3ZD88
Vous êtes ici: