IL29 Protein (AA 1-200)

N° du produit ABIN7505594

Détail du produit

Antigène: IL29 (Interleukin 29 (IL29))

Type de proteíne: Recombinant

Attributs du protein: AA 1-200

Origine: Humain

Source: HEK-293 Cells

Séquence: Met1-Thr200

Attributs du produit: A DNA sequence encoding the Human IL-29 Protein(Q8IU54)(1-200)was expressed with a polyhistidine tag at the N-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: <1.0 EU per μg of the protein as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: IL29 (Interleukin 29 (IL29))

Autre désignation: IL-29 (IL29 Produits)

Synonymes: IL-29 Protein, IL29 Protein, interferon lambda 1 Protein, interferon lambda-1 Protein, interleukin 29 (interferon, lambda 1) Protein, IFNL1 Protein, LOC612539 Protein, IL29 Protein

Sujet:

Abbreviation: IL-29

Target Synonym: Interferon lambda-1,IFN-lambda-1,ytokine Zcyto21,Interleukin-29,IL29,IFNL1,ZCYTO21

Background: Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.

Poids moléculaire:

Calculated MW: 22 kDa

Observed MW: 28-35 kDa

UniProt: Q8IU54