BDNF Protein (AA 1-247) (His tag)
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- Antigène Voir toutes BDNF Protéines
- BDNF (Brain-Derived Neurotrophic Factor (BDNF))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-247
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette BDNF protéine est marqué à la His tag.
- Séquence
- Met1-Arg247
- Attributs du produit
- A DNA sequence encoding theHuman BDNF protein (P23560) (Met1-Arg247) was expressed with a C-His.
- Pureté
- > 85 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product BDNF Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Date de péremption
- 12 months
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- Antigène
- BDNF (Brain-Derived Neurotrophic Factor (BDNF))
- Autre désignation
- BDNF (BDNF Produits)
- Synonymes
- ANON2 Protein, BULN2 Protein, bdnf-A Protein, BDNF Protein, bdnf Protein, brain derived neurotrophic factor Protein, brain-derived neurotrophic factor Protein, brain-derived neurotrophic factor L homeolog Protein, brain-derived neurotrophic factor S homeolog Protein, BDNF Protein, Bdnf Protein, bdnf Protein, bdnf.L Protein, bdnf.S Protein
- Sujet
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Abbreviation: BDNF
Target Synonym: Abrineurin,ProBDNF
Background: Important signaling molecule that activates signaling cascades downstream of NTRK2.During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
- Poids moléculaire
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Calculated MW: 26 kDa
Observed MW: 26 kDa
- UniProt
- P23560
- Pathways
- Signalisation RTK, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
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