IGFBP3 Protein (AA 1-291) (His tag)
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- Antigène Voir toutes IGFBP3 Protéines
- IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-291
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette IGFBP3 protéine est marqué à la His tag.
- Séquence
- Met1-Lys291
- Attributs du produit
- A DNA sequence encoding theHuman IGFBP3 protein (P17936) (Met1-Lys291) was expressed with a C-His.
- Pureté
- > 80 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product IGFBP3 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Date de péremption
- 12 months
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- Antigène
- IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))
- Autre désignation
- IGFBP3 (IGFBP3 Produits)
- Synonymes
- BP-53 Protein, IBP3 Protein, AI649005 Protein, IGFBP-3 Protein, IGgfbp3 Protein, IGF-BP3 Protein, zgc:91788 Protein, IGFBP3 Protein, igfbp3 Protein, insulin like growth factor binding protein 3 Protein, insulin-like growth factor binding protein 3 Protein, IGFBP3 Protein, Igfbp3 Protein, igfbp3 Protein, IGFBP-3 Protein, LOC100305016 Protein
- Sujet
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Abbreviation: IGFBP3
Target Synonym: IBP-3,IGF-binding protein 3,IGFBP-3
Background: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R. Inhibits the positive effect of humanin on insulin sensitivity.Promotes testicular germ cell apoptosis.
- Poids moléculaire
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Calculated MW: 32.5 kDa
Observed MW: 38-42 kDa
- UniProt
- P17936
- Pathways
- Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Growth Factor Binding
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