Frataxin Protein (FXN) (AA 42-210) (His tag)
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- Antigène Voir toutes Frataxin (FXN) Protéines
- Frataxin (FXN)
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 42-210
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette Frataxin protéine est marqué à la His tag.
- Séquence
- Leu42-Ala210
- Attributs du produit
- A DNA sequence encoding the Human FXN protein (Q16595) (Leu42-Ala210) was expressed with a C-His.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product FXN Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Date de péremption
- 12 months
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- Antigène
- Frataxin (FXN)
- Autre désignation
- Frataxin (FXN Produits)
- Synonymes
- zgc:158218 Protein, LOC100284365 Protein, BcDNA:AT09528 Protein, CG8971 Protein, DFH Protein, Dfh Protein, Dmel\\CG8971 Protein, X25 Protein, dfh Protein, CyaY Protein, FA Protein, FARR Protein, FRDA Protein, RGD1565754 Protein, Frda Protein, frataxin Protein, fxn Protein, LOC100284365 Protein, TVAG_182150 Protein, fh Protein, FTX1 Protein, FXN Protein, Fxn Protein
- Sujet
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Abbreviation: Frataxin,FXN
Target Synonym: Frataxin,mitochondrial,Friedreich ataxia protein,FXN,FRDA,X25,Frataxin intermediate form
Background: Frataxin intermediate form can cleave by mitochondrial processing peptidase(MPP) to the mature frataxin. Frataxin is a nuclear-encoded mitochondrial protein highly conserved in prokaryotes and eukaryotes. Its deficiency was initially described as the phenotype of Friedreich's ataxia, an autosomal recessive disease in humans. Although several functions have been described for frataxin, that is, involvement in Fe-S cluster and heme synthesis, energy conversion and oxidative phosphorylation, iron handling and response to oxidative damage, its precise function remains unclear. Although there is a general consensus on the participation of frataxin in the maintenance of cellular iron homeostasis and in iron metabolism, this protein may have other specific functions in different tissues and organisms.
- Poids moléculaire
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Calculated MW: 18.48 kDa
Observed MW: 21 kDa
- UniProt
- Q16595
- Pathways
- Transition Metal Ion Homeostasis, Regulation of Cell Size
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