Calnexin Protein (CANX) (AA 1-481) (His tag)
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- Antigène Voir toutes Calnexin (CANX) Protéines
- Calnexin (CANX)
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-481
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette Calnexin protéine est marqué à la His tag.
- Séquence
- Met1-Pro481
- Attributs du produit
- A DNA sequence encoding the Human CANX protein (P27824) (Met1-Pro481) was expressed with a C-His.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product CANX Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Date de péremption
- 12 months
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- Antigène
- Calnexin (CANX)
- Autre désignation
- Calnexin (CANX Produits)
- Synonymes
- CNX Protein, IP90 Protein, P90 Protein, 1110069N15Rik Protein, AI988026 Protein, Cnx Protein, D11Ertd153e Protein, canx Protein, clgn Protein, clnx Protein, cnx Protein, PP90 Protein, zgc:63524 Protein, wu:fe06b12 Protein, CANX Protein, calnexin Protein, CalNeXin Protein, calnexin L homeolog Protein, CANX Protein, Canx Protein, cnx-1 Protein, canx.L Protein, canx Protein, LOC100283947 Protein
- Sujet
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Abbreviation: Calnexin,CANX
Target Synonym: Calnexin,IP90,Major Histocompatibility Complex Class I Antigen-Binding Protein p88,p90,CANX
Background: Calnexin/CANX is a single-pass type I membrane protein which belongs to the calreticulin family. It consists of a large N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short (90 residues), acidic cytoplasmic tail. The function of calnexin is to retain unfolded or unassembled N-linked glycoproteins in the endoplasmic reticulum. Calnexin is a calcium-binding protein that interacts briefly with newly synthesized glycoproteins in the endoplasmic reticulum. Calnexin may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. Calnexin seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Calnexin dwindles with aging and might contribute to a cytoprotection in an array of human age-related diseases.
- Poids moléculaire
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Calculated MW: 52.8 kDa
Observed MW: 60 kDa
- UniProt
- P27824
- Pathways
- Signalisation MAPK, Thyroid Hormone Synthesis
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