Ephrin A5 Protein (EFNA5) (AA 1-203) (His tag)

N° du produit ABIN7505649

Détail du produit

Antigène: Ephrin A5 (EFNA5)

Type de proteíne: Recombinant

Attributs du protein: AA 1-203

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Ephrin A5 protéine est marqué à la His tag.

Séquence: Met1-Asn203

Attributs du produit: A DNA sequence encoding the Human EFNA5 protein (P52803) (Met1-Asn203) was expressed with a C-His.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: Ephrin A5 (EFNA5)

Autre désignation: Ephrin-A5 (EFNA5 Produits)

Synonymes: EFNA5 Protein, af1 Protein, efl5 Protein, rags Protein, eplg7 Protein, lerk7 Protein, AL-1 Protein, AV158822 Protein, EFL-5 Protein, Ephrin-A5 Protein, Epl7 Protein, LERK-7 Protein, RAGS Protein, Lerk7 Protein, AF1 Protein, EFL5 Protein, EPLG7 Protein, GLC1M Protein, LERK7 Protein, ephrin A5 Protein, EFNA5 Protein, efna5 Protein, Efna5 Protein

Sujet:

Abbreviation: Ephrin-A5,EFNA5

Target Synonym: Ephrin-A5,EPLG7,LERK7,EFNA5,LERK-7,EPH-related receptor tyrosine kinase ligand 7,AL-1

Background: Ephrin-A5 (EFNA5) belongs to the ephrin family,contains 1 ephrin RBD (ephrin receptor-binding) domain. Ephrin-A5 is a cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. It binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The interaction of EFNA5 with EPHA5 also mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion. Cognate/functional ligand for EPHA7, their interaction regulates brain development modulating cell-cell adhesion and repulsion.

Poids moléculaire:

Calculated MW: 32.67 kDa

Observed MW: 32 kDa

UniProt: P52803

Pathways: Signalisation RTK