IGHG4 Protein (AA 99-327) (His tag,Fc Tag)

N° du produit ABIN7505663

Détail du produit

Antigène: IGHG4 (Immunoglobulin Heavy Constant gamma 4 (G4m Marker) (IGHG4))

Type de proteíne: Recombinant

Attributs du protein: AA 99-327

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette IGHG4 protéine est marqué à la His tag,Fc Tag.

Séquence: Glu99-Lys327

Attributs du produit: A DNA sequence encoding the Human IgG4 protein (P01861) (Glu99-Lys327) was expressed with a C-His.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: IGHG4 (Immunoglobulin Heavy Constant gamma 4 (G4m Marker) (IGHG4))

Autre désignation: IGHG4 (IGHG4 Produits)

Synonymes: immunoglobulin heavy constant gamma 4 (G4m marker) Protein, IGHG4 Protein

Sujet:

Abbreviation: IgG4-Fc

Target Synonym: Ig gamma-4 chain C region,IgG4 Fc,IGHG4

Background: SCN3B (sodium channel, voltage-gated, type III, beta ,human IgG1-Fc chimera) belongs to the sodium channel auxiliary subunit SCN3B family. It contains 1 Ig-like C2-type (immunoglobulin-like) domain. Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. SCN3B gene encodes one member of the sodium channel beta subunit gene family, and influences the inactivation kinetics of the sodium channel. Two alternatively spliced variants, encoding the same protein, have been identified. Defects in SCN3B are the cause of Brugada syndrome type 7. A tachyarrhythmia characterized by right bundle branch block and ST segment elevation on an electrocardiogram. It can cause the ventricles to beat so fast that the blood is prevented from circulating efficiently in the body. When this situation occurs (called ventricular fibrillation), the individual will faint and may die in a few minutes if the heart is not reset.

Poids moléculaire:

Calculated MW: 25.08 kDa

Observed MW: 35 kDa

UniProt: P01861