TIMP1 Protein (AA 1-207) (His tag)

N° du produit ABIN7505680

Détail du produit

Antigène: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-207

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette TIMP1 protéine est marqué à la His tag.

Séquence: Met1-Ala207

Attributs du produit: A DNA sequence encoding the Human TIMP-1 protein (P01033) (1-207) was expressed with a C-His.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Autre désignation: TIMP-1 (TIMP1 Produits)

Synonymes: TIMP-1 Protein, TIMP1 Protein, DKFZp468A0912 Protein, CLGI Protein, EPA Protein, EPO Protein, HCI Protein, TIMP Protein, Timp Protein, Clgi Protein, TIMP metallopeptidase inhibitor 1 Protein, tissue inhibitor of metalloproteinase 1 Protein, TIMP1 Protein, Timp1 Protein

Sujet:

Abbreviation: TIMP-1

Target Synonym: Metalloproteinase Inhibitor 1,Erythroid-Potentiating Activity,EPA,Fibroblast collagenase Inhibitor,Collagenase Inhibitor,Tissue Inhibitor of Metalloproteinases 1,TIMP-1,TIMP1,CLGI,TIMP,CLGI,EPA,EPO,HCI

Background: Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) is a member of TIMP family. The homologous proteins of TIMPs regulate the activity of matrix metalloproteinases (MMPs), including inhibition of active MMPs, proMMP activation, cell growth promotion, matrix binding, inhibition of angiogenesis and the induction of apoptosis. Timp-1 complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. It also mediates erythropoiesis in vitro, but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. It is known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13, and MMP-16, without MMP-14.

Poids moléculaire:

Calculated MW: 22.66 kDa

Observed MW: 30 kDa

UniProt: P01033