Sclerostin Protein (SOST) (AA 1-213) (His tag)
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- Antigène Voir toutes Sclerostin (SOST) Protéines
- Sclerostin (SOST)
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-213
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette Sclerostin protéine est marqué à la His tag.
- Séquence
- Met1-Tyr213
- Attributs du produit
- A DNA sequence encoding the Human SOST protein (Q9BQB4) (Met1-Tyr213) was expressed with a C-His.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product SOST Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Date de péremption
- 12 months
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- Antigène
- Sclerostin (SOST)
- Autre désignation
- Sclerostin (SOST Produits)
- Synonymes
- LOC100313724 Protein, CDD Protein, VBCH Protein, 5430411E23Rik Protein, sclerostin Protein, LOC100313724 Protein, SOST Protein, Sost Protein
- Sujet
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Abbreviation: Sclerostin,SOST
Target Synonym: CDD,DAND6,SOST1,VBCH
Background: Sclerostin, also known as SOST, is a member of the Cerberus/DAN family of BMP antagonists. SOST is asecreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain. It shows sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. SOST is produced by the osteocyte and has anti-anabolic effects on bone formation. It is a negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
- Poids moléculaire
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Calculated MW: 23.32 kDa
Observed MW: 35 kDa
- UniProt
- Q9BQB4
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