BTN3A1 Protein (AA 1-254) (His tag)

N° du produit ABIN7505706

Détail du produit

Antigène: BTN3A1 (Butyrophilin, Subfamily 3, Member A1 (BTN3A1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-254

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette BTN3A1 protéine est marqué à la His tag.

Séquence: Met1-Gly254

Attributs du produit: A DNA sequence encoding the Human BTN3A1,CD277 protein (O00481) (Met1-Gly254) was expressed with a C-His.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: BTN3A1 (Butyrophilin, Subfamily 3, Member A1 (BTN3A1))

Autre désignation: BTN3A1 (BTN3A1 Produits)

Synonymes: BT3.1 Protein, BTF5 Protein, CD277 Protein, BTN3A1 Protein, butyrophilin subfamily 3 member A1 Protein, BTN3A1 Protein, LOC100447925 Protein

Sujet:

Abbreviation: BTN3A1,CD277

Target Synonym: Butyrophilin subfamily 3 member A1,CD277,BTN3A1,BTF5

Background: Butyrophilin Subfamily 3 Member A1 (BTN3A1/CD277) is a type I transmembrane glycoprotein member of the Ig superfamily. It is expressed on a wide variety of immune cells. Similar to BTN3A2 and BTN3A3, BTN3A1 is composed of an extracellular N-terminal IgV and a membraneproximal IgC domain followed by a transmembrane domain and a cytoplasmic tail. These Ig domains are also found in B7 family costimulatory molecules, suggesting structural and functional similarities between the two protein families. BTN3A1 acts as a critical protein for the activation of Vγ9Vδ2 T cells following detection of distressed cells. The anti-tumor responses of Vγ9Vδ2 T cells may be enhanced with agonistic anti-BTNA3 antibodies.

Poids moléculaire:

Calculated MW: 27.83 kDa

Observed MW: 30 kDa

UniProt: O00481

Pathways: Activated T Cell Proliferation