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CA9 Protein (AA 1-390) (His tag)

CA9 Origine: Souris Hôte: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7505747
  • Antigène Voir toutes CA9 Protéines
    CA9 (Carbonic Anhydrase IX (CA9))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-390
    Origine
    • 19
    • 4
    • 3
    • 2
    Souris
    Source
    • 19
    • 6
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette CA9 protéine est marqué à la His tag.
    Séquence
    Met1-Asp390
    Attributs du produit
    A DNA sequence encoding the Mouse CA9 protein (Q8VHB5) (Met1-Asp390) was expressed with a C-His.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product CA9 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Date de péremption
    12 months
  • Antigène
    CA9 (Carbonic Anhydrase IX (CA9))
    Autre désignation
    Carbonic Anhydrase 9 (CA9 Produits)
    Synonymes
    CA9 Protein, CAIX Protein, Ca9 Protein, MN/CA9 Protein, MN Protein, carbonic anhydrase 9 Protein, CA9 Protein, CAH9 Protein, Car9 Protein
    Sujet

    Abbreviation: Carbonic Anhydrase 9;CA9

    Target Synonym: RP23-195K8.9;CAIX;Ca9;MN/CA9

    Background: Carbonic anhydrases 9 (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. Cas are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA IX protein is expressed primarily in carcinoma cells lines, and the expression is cell density dependent and has been shown to be strongly induced by hypoxia, accordingly facilitates adaptation of tumor cells to hypoxic conditions. It is involved in tumorigenesis through many pathways, such as pH regulation and cell adhesion control. CA IX is used as a marker of tumor hypoxia and as a new therapeutic target for many human carcinomas and cancers.

    Poids moléculaire

    Calculated MW: 42.79 kDa

    Observed MW: 50 kDa

    UniProt
    Q8VHB5
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