CA9 Protein (AA 1-390) (His tag)
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- Antigène Voir toutes CA9 Protéines
- CA9 (Carbonic Anhydrase IX (CA9))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-390
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Origine
- Souris
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette CA9 protéine est marqué à la His tag.
- Séquence
- Met1-Asp390
- Attributs du produit
- A DNA sequence encoding the Mouse CA9 protein (Q8VHB5) (Met1-Asp390) was expressed with a C-His.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product CA9 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Date de péremption
- 12 months
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- Antigène
- CA9 (Carbonic Anhydrase IX (CA9))
- Autre désignation
- Carbonic Anhydrase 9 (CA9 Produits)
- Synonymes
- CA9 Protein, CAIX Protein, Ca9 Protein, MN/CA9 Protein, MN Protein, carbonic anhydrase 9 Protein, CA9 Protein, CAH9 Protein, Car9 Protein
- Sujet
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Abbreviation: Carbonic Anhydrase 9;CA9
Target Synonym: RP23-195K8.9;CAIX;Ca9;MN/CA9
Background: Carbonic anhydrases 9 (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. Cas are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA IX protein is expressed primarily in carcinoma cells lines, and the expression is cell density dependent and has been shown to be strongly induced by hypoxia, accordingly facilitates adaptation of tumor cells to hypoxic conditions. It is involved in tumorigenesis through many pathways, such as pH regulation and cell adhesion control. CA IX is used as a marker of tumor hypoxia and as a new therapeutic target for many human carcinomas and cancers.
- Poids moléculaire
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Calculated MW: 42.79 kDa
Observed MW: 50 kDa
- UniProt
- Q8VHB5
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